Matt Hendricks was born on June 17, 1981 in Blaine, Minnesota. Collegiately, he attended St. Cloud State of the WCHA, leading his team in goals as a junior.
Drafted by the Nashville Predators in 2000, Hendricks would make his pro debut in the AHL for the Milwaukee Admirals and begin a pro career that would see stops in Florida, Lowell, Rochester and Hershey, where he would help the Bears to the Calder Cup Final in 2007.
Hendricks signed with the Boston Bruins prior to the 2007-08 season and posted a career high 52 points for the Bruins' AHL affiliate in Providence. The following summer he was dealt to the Colorado Avalanche in exchange for Johnny Boychuk. He made his NHL debut on March 10, 2009 against the Atlanta Thrashers
On September 27, 2010, Hendricks signed a one year contract with the Washington Capitals.
After spending three seasons in Washington, Hendricks former team, the Nashville Predators, signed him to a four year contract on July 5, 2013. After struggling to start the 2013-14 season, Hendricks was traded to the Edmonton Oilers for Devan Dubnyk.