Guy Hebert was drafted by St. Louis in 1987, after his sophomore year at Hamilton College. He continued to play for Hamilton in the NCAA until 1989-90 when he reported to the Peoria Rivermen of the IHL. After two seasons in the minors, he was called up to the Blues in December 1991 and made his NHL debut against Buffalo. He played 13 games for the Blues that season and 29 for the Rivermen.
His time in Peoria earned him a spot on the IHL Second All-Star team, and a share of the James Norris Memorial Trophy for fewest goals against in the IHL. In 1992-93, he was full-time with the Blues as a back up to Curtis Joseph. The Mighty Ducks of Anaheim claimed Hebert in the 1993 Expansion Draft with their first pick, and he was their starting goalie for much of the next seven seasons.
In April 2000, Hebert became the first Mighty Duck to play 400 games. During his tenure with Anaheim, Hebert represented the United States in the 1994 World Championships and the 1996 World Cup. He also played in the NHL All-Star game in 1997. After the 1999-2000 season, Hebert signed with the New York Rangers as a free agent.