Born in Cranbrook, BC, Brad Lukowich played Tier II junior with the hometown Colts before joining the Kamloops Blazers of the WHL in 1992-93. The New York Islanders took him 90th overall in the 1994 NHL Entry Draft after contributing to a Memorial Cup championship. The young backliner then returned to junior for two more seasons and won a second Memorial Cup in 1995.
Before he had a chance to play for the Islanders, Lukowich was traded to the Dallas Stars in June, 1996. In his first two pro seasons he learned the ropes with the Michigan K-Wings of the IHL and was recalled briefly to Dallas. Lukowich also took part in eight playoff games during the team's drive to the Stanley Cup in 1999. In 1999-00, the rugged youngster averaged nearly 12 minutes in 60 games for the Stars before his breakthrough performance. Lukowich played 80 games for Dallas in 2000-01 and registered a fine +28 rating along with 14 points.
After one more season in Dallas, Lukowich was dealt to the Tampa Bay Lightning where he became an on-ice leader leading the Lightning to their first playoff appearance in six years in 2002-03 and helping them capture their first Stanley Cup title the following year.
In the summer of 2005, the former Kamloops Blazer signed as a free-agent with the New York Islanders and went on to spend the majority of the season on Long Island before being acquired by the New Jersey Devils at the NHL trading deadline.
Following parts of two seasons in New Jersey, Lukowich returned to the Tampa Bay Lightning signing a three-year contact as an unrestricted free agent. In his return to Tampa, Lukowich had one goal and six assists in 59 games. His stint in Tampa Bay came to a quick end when he was dealt to the San Jose Sharks in the summer of 2008.
In 2009-10, Brad was a victim of the numbers game in Vancouver and was unable to crack the Canucks' lineup. As a result he appeared in just 13 games for the club, spending the majority of the season with the AHL's Texas Stars.
On July 15, 2010, Lukowich inked a one-year deal with the Dallas Stars as an unrestricted free agent.