Born in Carlyle, Saskatchewan, Brenden Morrow scored 117 goals in 60 games for the Estevan Bruins of the SAHA before joining the Portland Winter Hawks of the WHL in 1995-96. A gritty forward who can put the puck in the net, Morrow amassed 127 goals in four years for the club and was a WHL First Team All-Star in 1998-99. The 25th overall selection of the Dallas Stars in the 1997 NHL Entry Draft, Morrow help Portland capture a Memorial Cup title in 1999, before making his NHL debut in 2000-01.
As a rookie Morrow went on to score 14 goals and finished the season with 33 points. After a strong rookie campaign, Morrow registered 20 goals and was a +18 in 2000-01 while taking on a more substantial role with the Stars. A strong skater, Morrow set a career high in goals in 2002-03 with 21 before eclipsing that total in 2003-04, when he tallied 25 goals and finished the season with 49 points.
During the NHL lockout, Morrow spent his time competing with the Oklahoma City Blazers, where in 19 games, he collected 22 points. He returned to the NHL the following season and went on to set a new career-high in assists (42) and points (65).
His production and leadership with the Stars was recognized just prior to the start of the 2006-07 season as Morrow was named the club's new team captain. In his first season as captain, Morrow would pick up where he left off offensively, but miss 33 games due to an injury to his right wrist. A healthy Morrow returned in 2007-08 and went on to lead the Stars in goals scored (32) while he set new career highs in assists (42)and points (74).
On the international stage, Morrow was a member of Canada's World Junior silver medal team in 1999, is a four-time member of its World Championship team (2001, 2002, 2004 and 2005) and was part of the Canadian team that captured gold on home soil at the 2010 Olympic Winter Games in Vancouver.
On March 24, 2013, Morrow's time in Dallas would come to an end. The Stars' captain agreed to waive his no-trade clause and he was traded to the Pittsburgh Penguins.
Morrow's time in Pittsburgh would be short-lived. After finishing the season with the Penguins, Morrow would become and unrestricted free agent. On September 23, 2013, he signed a 1-year deal with the St. Louis Blues.