Born in Edmonton, Alberta, Tyson Nash played Junior B with Sherwood Park before joining the Kamloops Blazers of the WHL in 1990-91. The feisty winger played on the team's Memorial Cup wins in 1992, 1994 and 1995. In the process he became one of only three players to win three national junior titles, joining teammates Darcy Tucker and Ryan Huska.
In 1994, Nash was selected 247th overall by the Vancouver Canucks in the 1994 NHL Entry Draft. Nash spent some time with the ECHL's Raleigh Ice Caps and developed his game with the Syracuse Crunch of the AHL for three years before signing as a free agent with the St. Louis Blues in the summer of 1998.
Nash saw limited action with the Blues during the 1998-99 season, however was a key figure with the team's AHL affiliate in Worcester. In 1999-00, St. Louis utilized him as an emotional grinder and penalty killer which became his niche in the NHL and he filled that role for five seasons before being dealt to the Phoenix Coyotes in the summer of 2003.
Nash would compete in two seasons with the Coyotes before he was acquired by the Toronto Maple Leafs in exchange for Mikael Tellqvist.